Pyrrolidine was used as a catalyst for the simple, convenient, and highly efficient synthesis of dihydropyrano[2,3-c]pyrazole
derivatives. Four-component one-pot reactions of β-ketoester, hydrazine, ethyl glyoxalate or ethyl pyruvate, and malononitrile in ethanol
under reflux conditions led to excellent yields of 79%-94%.
Keywords: Dihydropyrano[2, 3-c]pyrazole, multi-component reactions, one-pot synthesis, Pyrrolidine, Triazolo[4, 3-a]pyrimidines.
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