Abstract
We report a convenient access to tertiary carbinamines bearing a gem-diaryl group by Cu-catalyzed aryl Grignard addition to cyclic sulfamidate imines and sulfamide imines. The synthesis of hetero-functionalized 1,2-ethylene derivatives by ring-opening of the resulting sulfamidates is also described.
Keywords: Copper triflate, gem-diaryl group, Grignard addition, sulfamidate, tertiary carbinamine.
Current Organic Synthesis
Title:Entry to Tertiary Carbinamines Bearing a gem-Diaryl Group by Copper-Catalyzed Grignard Addition to Cyclic Sulfamidate Imines.
Volume: 10 Issue: 5
Author(s): Arigala Pitchaiah, Miri Kim, In Taek Hwang and Kee-In Lee
Affiliation:
Keywords: Copper triflate, gem-diaryl group, Grignard addition, sulfamidate, tertiary carbinamine.
Abstract: We report a convenient access to tertiary carbinamines bearing a gem-diaryl group by Cu-catalyzed aryl Grignard addition to cyclic sulfamidate imines and sulfamide imines. The synthesis of hetero-functionalized 1,2-ethylene derivatives by ring-opening of the resulting sulfamidates is also described.
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Cite this article as:
Pitchaiah Arigala, Kim Miri, Hwang Taek In and Lee Kee-In, Entry to Tertiary Carbinamines Bearing a gem-Diaryl Group by Copper-Catalyzed Grignard Addition to Cyclic Sulfamidate Imines., Current Organic Synthesis 2013; 10 (5) . https://dx.doi.org/10.2174/15701794113109990067
DOI https://dx.doi.org/10.2174/15701794113109990067 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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