Abstract
Alkylboronate derivatives are important intermediates in organic synthesis and medicinal chemistry. The research of synthesizing alkylboronic acid derivatives has attracted great attention of chemists and many papers have reported various methods for preparing alkylboronates based on transition-metal-catalyzed hydroboration. In this review, we summarize the methods of synthesizing alkylboronate derivatives with different catalysts, such as Rhodium, Palladium, Copper, Iridium, Iron, Magnesiu, Platinum, Nickel and so on. Pinacolborane, bispinacolatodiboron and catecholborane are applied as important reagents and substrates with different skeleton structures and functional groups are employed to prepare diversity of alkylboronates.
Keywords: Alkylboronate, alkylboronic derivatives, catalyst, hydroboration, transition metal.
Current Organic Synthesis
Title:Alkylboronate Synthesis Based on Transition Metal-Catalyzed Hydroboration.
Volume: 10 Issue: 5
Author(s): Saipeng Huang, Yuanchao Xie, Shaolei Wu, Meirong Jia, Junhua Wang, Wenfeng Xu and Hao Fang
Affiliation:
Keywords: Alkylboronate, alkylboronic derivatives, catalyst, hydroboration, transition metal.
Abstract: Alkylboronate derivatives are important intermediates in organic synthesis and medicinal chemistry. The research of synthesizing alkylboronic acid derivatives has attracted great attention of chemists and many papers have reported various methods for preparing alkylboronates based on transition-metal-catalyzed hydroboration. In this review, we summarize the methods of synthesizing alkylboronate derivatives with different catalysts, such as Rhodium, Palladium, Copper, Iridium, Iron, Magnesiu, Platinum, Nickel and so on. Pinacolborane, bispinacolatodiboron and catecholborane are applied as important reagents and substrates with different skeleton structures and functional groups are employed to prepare diversity of alkylboronates.
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Cite this article as:
Huang Saipeng, Xie Yuanchao, Wu Shaolei, Jia Meirong, Wang Junhua, Xu Wenfeng and Fang Hao, Alkylboronate Synthesis Based on Transition Metal-Catalyzed Hydroboration., Current Organic Synthesis 2013; 10 (5) . https://dx.doi.org/10.2174/15701794113109990060
DOI https://dx.doi.org/10.2174/15701794113109990060 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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