Current Organic Chemistry


Novel Drug Delivery Magnetite Nano-systems Used in Antimicrobial Therapy

Author(s): Alina Maria Holban, Alexandru Mihai Grumezescu, Monica Cartelle Gestal, Laurentiu Mogoanta and George Dan Mogosanu

Affiliation: University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, Department of Science and Engineering of Oxide Materials and Nanomaterials, Polizu Street no 1-7, 011061 Bucharest, Romania.


As traditional antimicrobial approaches become less effective, novel alternatives in treating resistant infections are required. Nanotechnology is an emerging field recently exploited for its numerous biomedical applications. Magnetic nanoparticles has proved their anti-microbial properties when used as drug delivery systems and recent proclivity propose Fe3O4 derived nanosystems as efficient anti-biofilm development indicators. This paper discusses the most recent findings regarding the usage of magnetic nanoparticles as potent drug delivery shuttles in anti-microbial approaches.

Keywords: Magnetite nanoparticles, antimicrobial therapy, drug delivery, drug targeting, nonpolar magnetite, polar magnetite.

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Article Details

Page: [185 - 191]
Pages: 7
DOI: 10.2174/13852728113176660142
Price: $58