Current Stem Cell Research & Therapy

Anthony Atala  
Wake Forest University School of Medicine,
Medical Center Boulevard
Winston Salem, NC 27157
USA

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A Review of Preclinical and Clinical Studies Using Synthetic Materials for Meniscus Replacement.

Author(s): Umile Giuseppe Longo, Giacomo Rizzello, Alessandra Berton, Caterina Fumo, Giulio Battaglia, Wasim S. Khan, Vincenzo Denaro.

Abstract:

The emerging field of tissue engineering holds the promise to use bio-materials for meniscus injury repair, namely scaffold or meniscus implant. Many implants have been studied and several studies have been conducted to verify the safety and quality of scaffolds. Preliminary data support the idea that synthetic implants can provide an alternative to menyscectomy helping to preserve the cartilage and preventing arthritis in patient with menisci injuries. However, the prevalence of postoperative complications varies within studies. Further investigations are required to evaluate the role of these materials in the clinical practice.

Keywords: Biomaterials, clinical studies, meniscus, preclinical studies, scaffolds, synthetic materials, tissue engineering.

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Article Details

VOLUME: 8
ISSUE: 6
Year: 2013
Page: [438 - 443]
Pages: 6
DOI: 10.2174/1574888X1130800061
Price: $58