Letters in Organic Chemistry

Gwilherm Evano
Free University of Brussels
Brussels
Belgium

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TBAOH Mediated: An Efficient and Simple Procedure for Alkylation of Alcohols, Phenols and Thiols Under Neat Aqueous Conditions

Author(s): Mohammad Soleiman-Beigi, Mosstafa Kazemi, Reza Aryan, Lotfi Shiri.

Abstract:

Aqueous tetra-n-butyl ammonium hydroxide solution (TBAOH) has been used as a green reaction medium and efficient catalyst for the O-alkylation of alcohols and phenols as well as S-alkylation of thiols under a novel, mild and convenient procedure. Herein, TBAOH has been used as a strong base, medium of reaction and phase transfer reagent.

Keywords: Tetra-n-butyl ammonium hydroxide, ethers, thioethers, neat condition, alkylation.

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Article Details

VOLUME: 11
ISSUE: 5
Year: 2014
Page: [321 - 326]
Pages: 6
DOI: 10.2174/15701786113106660077
Price: $58