Insect Inducible Antimicrobial Peptides and their Applications

Author(s): Reyhaneh Ezzati-Tabrizi, Naser Farrokhi, Reza Talaei-Hassanloui, Seyed Mehdi Alavi, Vahid Hosseininaveh.

Journal Name: Current Protein & Peptide Science

Volume 14 , Issue 8 , 2013

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Abstract:

Antimicrobial peptides (AMPs) are found as important components of the innate immune system (host defense) of all invertebrates. These peptides can be constitutively expressed or induced in response to microbial infections. Indeed, they vary in their amino acid sequences, potency and antimicrobial activity spectra. The smaller AMPs act greatly by disrupting the structure or function of microbial cell membranes. Here, the insect innate immune system with emphasis on inducible antimicrobial peptide properties against microbial invaders has been discussed.

Keywords: Cationic peptides, humoral immune system, inducible antimicrobial peptide, microbial cell membranes, microbial infections, signal transduction pathways.

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Article Details

VOLUME: 14
ISSUE: 8
Year: 2013
Page: [698 - 710]
Pages: 13
DOI: 10.2174/1389203711209070620
Price: $58

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