A series of dihydropyridine analogous was synthesized and evaluated for anticonvulsant activity using PTZ
animal model. The main strategies are introducing a non-classical dihydropyridine like structure as anti-seizure agent.
Some compounds showed significant anticonvulsant activity in comparison with the control group.
Keywords: Seizure, Anticonvulsant, Hexahydroquinoline derivative, 1, 4-dihydropyrimidine derivative, PTZ animal model,
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