Toward a Better Understanding of Pharmacokinetics of Nanomaterials

Author(s): Chengke Zhang, Qiu Zhang, Yi Zhang, Bing Yan.

Journal Name: Current Pharmaceutical Design

Volume 19 , Issue 37 , 2013

Abstract:

Nanotechnology has promising applications in biomedicine, such as in drug delivery, diagnosis, and tissue engineering. The pharmacokinetics of nanomaterials significantly affects their biological behavior in vivo, affecting their biomedical applications and potential nanotoxicity. In this review, we highlight some recent advances in the pharmacokinetic studies of representative nanomaterials. We focus on the relationships between the physicochemical properties of nanomaterials and physiological consequences.

Keywords: Nanomaterials, pharmacokinetics, absorption, distribution, metabolism, excretion.

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Article Details

VOLUME: 19
ISSUE: 37
Year: 2013
Page: [6667 - 6680]
Pages: 14
DOI: 10.2174/1381612811319370010
Price: $58

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