The Asymmetric Synthesis of Spiro-Sultam-oxindoles

Author(s): Li-Na Fu.

Journal Name: Letters in Organic Chemistry

Volume 11 , Issue 1 , 2014

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Abstract:

Novel optically active spiro-sultam-oxindole compounds with middle yields and excellent stereoselectivites were prepared through consecutive N-mesylation/cyclization reactions. The enantioselectivities of the reactants could transfer to the desired products completely.

Keywords: Oxindole, sultam, asymmetric synthesis, mesylation, cyclization.

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Article Details

VOLUME: 11
ISSUE: 1
Year: 2014
Page: [13 - 17]
Pages: 5
DOI: 10.2174/15701786113106660071

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PDF: 17