Hyperthermophilic Enzymes: Their Potential in Biotechnology
Luisa Maurelli and Alessandra Morana
Affiliation: Institute of Protein Biochemistry, National Research Council of Italy, Via Pietro Castellino 111, 80131 Naples, Italy.
Keywords: Alpha-amylase, cellulase, esterase, hyperthermophilic enzymes, lipase, pullulanase, xylanase.
Enzymes from hyperthermophiles exhibit elevated thermostability and among them, cellulases, amylases,
xylanases, proteases, pectinases, lipases and esterases represent extremozymes with great potential for application in
various biotechnological processes.
Currently, among the microorganisms commercially exploited, there are only a few examples of extremophiles. However,
the interest towards their biocatalysts that is continuously increasing as a result of new developments in cultivation of
extremophiles and success in the cloning and expression of their genes in mesophilic hosts, will increase their spread. In
this review, special attention has been dedicated to the major classes of enzymes of potential interest in biotechnological
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