Imidazoles as Promising Scaffolds for Antibacterial Activity: A Review

Author(s): Nidhi Rani , Ajay Sharma , Randhir Singh .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 13 , Issue 12 , 2013

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Abstract:

In the last few decades, a lot of work has been done on heterocycles, especially the imidazole ring, to obtain a scaffold with potential pharmacological properties such as antibacterial, antifungal, anticancer, antiviral, antidiabetic and others, with lesser side effects. The search for new biologically active imidazoles continues to be an interesting area of investigation in medicinal chemistry. The present paper aims to bring together and discuss the wealth of information on antibacterial profile of imidazoles. So it can be employed for future development to obtain new potent drug molecules.

Keywords: Bacteria, Antibacterial agent, Imidazole, Structure activity relationship study.

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Article Details

VOLUME: 13
ISSUE: 12
Year: 2013
Page: [1812 - 1835]
Pages: 24
DOI: 10.2174/13895575113136660091
Price: $58

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