Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones

Author(s): Akbar Mobinikhaledi, Alireza Khajeh Amiri.

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 10 , 2013

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A high efficient and environmentally friendly procedure for the production of bis thiazolidinones has been developed. This synthetic approach involves the simple condensation of an appropriate dialdehyde and N,N'-diarylthioureas with chloroacetyl chloride in eutectic salts as a promoter and solvent at 80 °C. All products were obtained in good to excellent yields. Structures of these compounds were established on the basis of IR, 1H-NMR, 13C-NMR and by elemental analysis.

Keywords: Bis thiazolidinone heterocycles, choline chloride, green chemistry, ionic liquids, multicomponent reactions, one-pot synthesis.

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Article Details

Year: 2013
Page: [764 - 769]
Pages: 6
DOI: 10.2174/157017861131000059
Price: $65

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