Alkaloids are interesting groups of natural products with important biological properties, but naturally available
alkaloids are insufficient for biological studies. Therefore, the demand for higher amounts of alkaloids made research
community to synthesize alkaloids by innovative techniques. The importance of asymmetric reactions for scientific community
to obtain enantiomerically pure compounds with good yield and diastereomeric excess (de) or enantiomeric excess
(ee) by different strategies of asymmetric induction is emphasized in this review. In addition, importance have been given
to discuss on biologically important alkaloids, their skeleton synthesis, intermediates and total synthesis with different
strategies mainly based on chiral auxiliaries, chiral reagents and chiral metal ligand based catalysts.
Keywords: Asymmetric synthesis, alkaloids, asymmetric induction, Chiral auxiliaries, Chiral catalyst, Chiral reagents.
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