Current Organocatalysis

Bimal K. Banik
Vice President of Research & Education Development
Community Health Systems of South Texas (CHSST)
Edinburg, Texas
USA

Back

Nitrogen Bound Polymers as Heterogeneous Basic Catalysts for Diastereoselective Henry Reaction in Aqueous Medium

Author(s): Parishmita Sarma, Pinky Gogoi and Ruli Borah

Affiliation: Department of Chemical Sciences, Tezpur University (A Central University), Napaam, Tezpur 784028, Assam, India.

Keywords: Aqueous medium, ambient temperature, cyclic transition state mechanism, diastereoselective, environmentally benign, heterogeneous catalyst, Henry reaction, high yields, syn-2-Nitroalkanols, Poly-4-vinylpyridine, reusable catalyst.

Graphical Abstract:


Abstract:

Poly(4-vinylpyridine) (P4VP) has been found as an efficient recyclable heterogeneous Lewis base catalyst for the diastereoselective synthesis of syn-2-nitroalkanols in aqueous medium. The 1H NMR and 13C NMR spectra of 2- nitroalkanols are utilized for determining the ratios of syn/anti stereoisomers. This protocol provides a simple greener path for the synthesis of 2-nitroalcohols in aqueous medium at ambient condition with high yields.

Reprint ePrint Rights & PermissionsPrintExport

Article Details

VOLUME: 1
ISSUE: 1
Page: [40 - 44]
Pages: 5
DOI: 10.2174/221333720101140529112354