Nitrogen Bound Polymers as Heterogeneous Basic Catalysts for Diastereoselective Henry Reaction in Aqueous Medium
Parishmita Sarma, Pinky Gogoi and Ruli Borah
Affiliation: Department of Chemical Sciences, Tezpur University (A Central University), Napaam, Tezpur 784028, Assam, India.
Poly(4-vinylpyridine) (P4VP) has been found as an efficient recyclable heterogeneous Lewis base catalyst for
the diastereoselective synthesis of syn-2-nitroalkanols in aqueous medium. The 1H NMR and 13C NMR spectra of 2-
nitroalkanols are utilized for determining the ratios of syn/anti stereoisomers. This protocol provides a simple greener path
for the synthesis of 2-nitroalcohols in aqueous medium at ambient condition with high yields.
Keywords: Aqueous medium, ambient temperature, cyclic transition state mechanism, diastereoselective, environmentally
benign, heterogeneous catalyst, Henry reaction, high yields, syn-2-Nitroalkanols, Poly-4-vinylpyridine, reusable catalyst.
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