The first entry to the 7,9,12b-triazabenzo[a]aceanthrylene ring system has been accomplished starting from
readily accessible 1-(2-bromoacetyl)-β-carboline via 5-aminocanthin-4-one in four steps. The 8-oxo derivative, which can
be considered as an annulated diazaacridone, exhibits significant antimicrobial properties.
Keywords: Canthin-4-one, β-Carboline, Diazaacridone, Skraup synthesis, Phthalimide, Antibacterial activity, Antifungal
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