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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of 1,4-dihydropyridine Derivatives via One Pot Multicomponent Condensation in Water

Author(s): Arash Ghorbani-Choghamarani and Masoomeh Norouzi

Volume 10, Issue 8, 2013

Page: [562 - 567] Pages: 6

DOI: 10.2174/15701786113109990012

Price: $65

Abstract

A facile and efficient one-pot preparation of a new series of 1,4-dihydropyridines has been reported via a threecomponent reaction of nano aluminum nitride, aromatic aldehydes and benzyl-3-oxobutanoate or 2-methoxyethyl-3- oxobutanoateat 80 °C in water. Using this methodology, Hantzsch1,4-dihydropyridine derivatives were synthesized in a simple pathway without the use of a catalyst or an organic solvent.

Keywords: 1, 4-Dihydropyridine, Hantzsch reaction, One-pot condensation, Multicomponent, Aluminum nitride.


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