Title:Halogen Exchange via a Halogenation of Diaryliodonium Salts with Cuprous Halide
VOLUME: 10 ISSUE: 8
Author(s):Jian Li, Li Liu, Dong Ding and Jiang-tao Sun
Affiliation:School of Pharmaceutical Engineering & Life Sciences, Chang Zhou University, Changzhou, 213164, P.R. China.
Keywords:Diaryliodonium salts, Halogenation, Cuprous halide, Aromatic halides, Iodoarenes.
Abstract:An efficient halogenation reaction has been developed with diaryliodonium salts and cuprous halides. Various
diaryliodonium salts 1 could perform the reaction with readily available CuBr or CuCl in CH3CN at 80°C, assembling
bromoarenes or chloroarenes in up to 92% yields. This provides us a method for the transformation from iodoarenes to
other haloarenes.
