TB Diagnostics – Old and New
In this review we will give an overview of current diagnostics tools excluding GeneXpert which will be
described elsewhere. We will focus on interesting advances in smear and culture methods alongside the application of
immunological assays such as antibody tests and interferon-gamma release assays. Mention will be made of recently
developed assays such as those for antigen-detection using urine as well as possible future directions of diagnostic
Keywords: Diagnosis, interferon-gamma release assay, lipoarabinomannan, microscopic observation broth-drug susceptibility
assay, smear microscopy, tuberculin skin test, tuberculosis.
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