The development of a solitary chest wall mass due to underlying malignant lymphoma is an uncommon clinical
presentation. Diffuse large B-cell lymphoma, a type of non-Hodgkin's lymphoma, can affect multiple organs including
the lungs and pleural space. In some instances, there may be preexisting inflammation such as a chronic pyothorax before
lymphoma arises in these locations. Diffuse large B-cell lymphoma may frequently disseminate to extranodal sites, but
involvement of the chest wall has been reported in nearly 100 cases. This report details an unusual presentation of diffuse
large B-cell lymphoma from an enlarging chest wall mass and an underlying lymphomatous pleural effusion.
Keywords: Chest wall mass, lymphoma, pleural effusion, pyothorax.
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