Omics Derived Networks in Bacteria
Understanding the cellular behavior from a systems perspective requires the identification of functional and
physical interactions among diverse molecular entities in a cell (i.e. DNA/RNA, proteins and metabolites). Powerful and
scalable technologies enabled the generation of genome-wide datasets that describe cellular systems by capturing the
interactions of their building blocks under different environmental stimuli. The most straightforward way to represent
such datasets is by means of molecular networks of which nodes correspond to molecular entities and edges to the
interactions amongst those entities. In this review we give an overview of the different functional and physical interaction
networks in bacteria that have been or potentially can be built by the integration of diverse omics datasets.
Keywords: Bacteria, dataintegration, molecular networks, network inference, omics data.
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