Multicomponent Reactions for the Synthesis of Functionalized Imidazoles

Author(s): Samereh Seyfi, Zinatossadat Hossaini, Faramarz Rostami-Charati.

Journal Name: Combinatorial Chemistry & High Throughput Screening

Volume 16 , Issue 8 , 2013

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Abstract:

An efficient synthesis of functionalized tetrahydroimidazoles via a one-pot tandem reaction between ninhydrin, primary alkylamines, arylisocyanates or arylisothiocyanates, acetylenic esters and triphenylphosphine is described.

Keywords: Arylisothiocyanates, dialkyl acetylenedicarboxylates, multi component reaction, ninhydrin, primary amine.

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Article Details

VOLUME: 16
ISSUE: 8
Year: 2013
Page: [652 - 656]
Pages: 5
DOI: 10.2174/13862073113169990005
Price: $58

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