Abstract
Clostridium difficile has become the most common infectious cause of healthcare-associated diarrhea, with serious morbidity, prolonged hospitalization and even death. Treatment of the disease utilizing today’s therapies does not guarantee a successful outcome. In the past decade, many new ideas and inventions have surfaced exploring different treatment strategies of Clostridium difficile associated diarrhea (CDAD). These treatments include antitoxins, novel antimicrobials, immunoglobulins and large inert synthetic compounds. In this paper, we survey of a number of representative patents issued from 2000 to the present targeting treatment of this difficult and dreaded disease.
Keywords: Bacterial toxin, Clostridium difficile, drug target, patents.
Recent Patents on Anti-Infective Drug Discovery
Title:A Surview of Recent Patents on Anti-Infective Therapy for Clostridium difficile
Volume: 8 Issue: 2
Author(s): Germine S. Soliman, Bechoi Saleib and Stephen J. Scholand
Affiliation:
Keywords: Bacterial toxin, Clostridium difficile, drug target, patents.
Abstract: Clostridium difficile has become the most common infectious cause of healthcare-associated diarrhea, with serious morbidity, prolonged hospitalization and even death. Treatment of the disease utilizing today’s therapies does not guarantee a successful outcome. In the past decade, many new ideas and inventions have surfaced exploring different treatment strategies of Clostridium difficile associated diarrhea (CDAD). These treatments include antitoxins, novel antimicrobials, immunoglobulins and large inert synthetic compounds. In this paper, we survey of a number of representative patents issued from 2000 to the present targeting treatment of this difficult and dreaded disease.
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Cite this article as:
Soliman S. Germine, Saleib Bechoi and Scholand J. Stephen, A Surview of Recent Patents on Anti-Infective Therapy for Clostridium difficile, Recent Patents on Anti-Infective Drug Discovery 2013; 8 (2) . https://dx.doi.org/10.2174/1574891X113089990016
DOI https://dx.doi.org/10.2174/1574891X113089990016 |
Print ISSN 1574-891X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4071 |
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