Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents)

Bahar Tunctan
Department of Pharmacology
Faculty of Pharmacy
Mersin University
Mersin, 33169
Turkey

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Measurement of Serum Monoamine Oxidase in Lichen Planus Patients and Its Clinical Significance

Author(s): Jianguo Huang, Qiying Gong, Guiming Li.

Abstract:

Objective: To study the role of serum Monoamine oxidase (MAO) in Lichen planus(LP). Methods: 82 cases of Lichen planus patients and 35 healthy controls were selected in the investigation. The total serum MAO levels were measured. Results: The levels of serum MAO in Lichen planus patients were significantly higher than those in healthy controls (P<0.01). The severity of Lichen planus was not correlated with serum MAO levels (r =0.4873, t=0.73, p>0.05). Conclusion: According to the findings, there might be a coincidence of MAO and lichen planus. However, further studies are required to clarify the immunological mechanisms which are responsible for MAO synthesis during immunoreaction.

Keywords: Lichen planus, measurement, mechanism, monoamine oxidase, serum.

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Article Details

VOLUME: 13
ISSUE: 1
Year: 2014
Page: [64 - 67]
Pages: 4
DOI: 10.2174/18715230113129990017