Tungstate Sulfuric Acid (TSA): A Green and Highly Efficient Catalyst for Novel and Known Polysubstituted Imidazoles Synthesis

Author(s): Bahador Karami, Khalil Eskandari, Mahboobeh Azizi.

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 10 , 2013

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Abstract:

Tungstate sulfuric acid (TSA) was composed of anhydrous sodium tungstate and chlorosulfonic acid with a new modified and efficient method. Catalyst was characterized by powdered X-ray diffraction (XRD), X-ray fluorescence (XRF), FT-IR spectroscopy and titration with NaOH (0.1 N). In the present study, highly efficient role of TSA as a catalyst in polysubstituted imidazoles synthesis as pharmaceuticaly important molecules via condensation between a wide range of aryl aldehydes, primary amines, benzil, and ammonium acetate in solventless conditions is reported. Therefore, new application of this catalyst to synthesize some novel imidazoles is introduced.

Keywords: Catalyst, green synthesis, imidazole, solvent-free, tungstate sulfuric acid, x-ray diffraction, x-ray fluorescence.

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Article Details

VOLUME: 10
ISSUE: 10
Year: 2013
Page: [722 - 732]
Pages: 11
DOI: 10.2174/15701786113109990044
Price: $65

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