Synthesis and Bio-Evaluation of Novel Salicylic Acid-Oriented Thiourea Derivatives with Potential Applications in Agriculture

Author(s): Shaowei Li, Huangyong Li, Xiufang Cao, Changshui Chen.

Journal Name: Letters in Drug Design & Discovery

Volume 11 , Issue 1 , 2014


A series of salicylic acid-oriented thiourea derivatives was conveniently synthesized via multi-steps mainly including alkylation, chlorination, nucleophilic substitution and addition reaction. The structure of all these newly synthesized derivatives was confirmed and characterized by IR, 1H NMR and MS. The preliminary bioassay indicated that these new compounds have some herbicidal activity or plant growth regulating activity against tested plants.

Keywords: Thiourea, Salicylic acid, Synthesis, Herbicidal activity, Plant growth regulating activity.

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Article Details

Year: 2014
Page: [98 - 103]
Pages: 6
DOI: 10.2174/15701808113109990045

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