A Simple and Highly Efficient Procedure for One-Pot Synthesis of 2- Azetidinones Using 3,5-Dinitrobenzoyl Chloride

Author(s): Alireza Darvishi, Maaroof Zarei, Mohammad Reza Akhgara.

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 9 , 2013

Become EABM
Become Reviewer

Abstract:

One-pot synthesis of 2-azetidinones has efficiently been carried out in excellent yields by treatment of imines and substituted acetic acids with 3,5-dinitrobenzoyl chloride in the presence of triethylamine. The method is remarkably convenient and pure products were obtained by simple crystallization.

Keywords: β-Lactam, 2-Azetidinone, Staudinger reaction, 3, 5-Dinitrobenzoyl chloride, Ketene, Imine.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 10
ISSUE: 9
Year: 2013
Page: [645 - 650]
Pages: 6
DOI: 10.2174/15701786113109990037

Article Metrics

PDF: 37