An overview of docking models of chain arylpiperazines to different subtypes of serotonin receptors belonging
to the GPCR family is presented. The theory of a ligand-receptor interaction has been briefly summarized. The review
covers more than twenty models, beginning with the early models of a ligand interaction with the 5-HT1A and 5-HT2A
receptor, and ending with a ligand-5-HT7 receptor docking studies.
Keywords: Docking, arylpiperazines, 5-HT1A receptor, 5-HT2A receptor, 5-HT7 receptor.
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