Recent Patents on Droplet-Based Microfluidics for Biomedical Application
Affiliation: Department of Biomedical Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.
Microfluidics has emerged as a novel platform for a diverse array of actual and potential applications ranging
from drug delivery, point-of-care diagnostic chips, to microreactors. Recent developments on microfabrication techniques
have opened the door to particle synthesis with precise control over the shapes, morphologies, and size distributions. This
paper presents the recent patents on microfluidic strategies for the production of particles, such as core-shell particles,
Janus particles (two-component or three-component) and non-spherical particles (ellipsoidal, discoid, rod). Advances in
the design of relevant microfluidic chips, fabrication process, and techniques for assembling component, are converging
towards biomedical applications of droplet-based microfluidic technologies
Keywords: Microfluidics, droplet, nanoparticles, microparticles, core-shell particles, Janus particles, non-spherical particles,
emulsification, multiemulsification, monodisperse, fusion, mixing, encapsulation, synthesis, bioassay, imaging.
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