Patent Review on Nanotechnology in Ocular Drug Delivery
Nandini Gupta, Shivangi Goel and Himanshu Gupta
Affiliation: Harrison School of Pharmacy, Auburn University, Auburn, AL 36830, USA.
Keywords: Ocular, nanoparticles, drug delivery, patents, nanoparticle laden in situ gel.
Numerous scientific efforts have been made till date to provide an efficient ocular drug delivery system, but
still it is challenging for pharmaceutical scientists.
Most of the ocular diseases are treated by topical drug application in the form of suspensions, solutions and ointments. But
because of various anatomical and pathophysiological barriers prevailing in the eye, these conventional dosage forms
suffer from the problem of poor ocular bioavailability. Nanotechnology emerges not only as a potential tool for ocular
drug delivery but also as a solution to drug targeting and improved bioavailability including various solubility related
This review provides an overview of various limitations associated with ocular drug delivery, summarizes recent findings
and patents on various nanotechnology products in ocular drug delivery.
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