Development of Safe and Economical Synthesis of Isoxazole

Author(s): Lakshmikant H. Nitlikar, Devanand B. Shinde.

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 9 , 2013

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Abstract:

Isoxazole is a five membered heterocyclic compound having various pharmacological actions. The new practical synthesis of isoxazole from the easily available malonadehyde tetraethyl acetal by avoiding the use of toxic reagent such as cadmium chloride under environment friendly conditions has been developed.

Keywords: Isoxazole, Malonaldehyde tetraethyl acetal, di (1, 3-dioxolan-2-yl) methane.

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Article Details

VOLUME: 10
ISSUE: 9
Year: 2013
Page: [637 - 639]
Pages: 3
DOI: 10.2174/15701786113109990032
Price: $65

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