Isoxazole is a five membered heterocyclic compound having various pharmacological actions. The new practical
synthesis of isoxazole from the easily available malonadehyde tetraethyl acetal by avoiding the use of toxic reagent
such as cadmium chloride under environment friendly conditions has been developed.
Keywords: Isoxazole, Malonaldehyde tetraethyl acetal, di (1, 3-dioxolan-2-yl) methane.
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