Synthesis of 1-substituted Tetrazoles Using CoFe2O4 Nanoparticles as a Magnetically Recoverable and Reusable Catalyst

Author(s): Siavash Bahari.

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 7 , 2013

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Nano CoFe2O4 is found to be efficient catalyst for synthesis of 1-substituted 1H-1,2,3,4-tetrazoles under solvent- free conditions. The significant advantages of this methodology are high yields, elimination of dangerous and harmful hydrazoic acid and simple work-up procedure. The catalyst was easily isolated from the reaction mixture by magnetic decantation using an external magnet and reused with no significant loss in its reactivity.

Keywords: CoFe2O4 Nanoparticles, Primary amines, triethyl orthoformate, 1-substituted 1H-1, 2, 3, 4-tetrazole.

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Article Details

Year: 2013
Page: [527 - 531]
Pages: 5
DOI: 10.2174/15701786113109990010
Price: $65

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