Title:Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction
VOLUME: 19 ISSUE: 28
Author(s):Rongrong Jing, Ming Cui, Huimin Wang and Shaoqing Ju
Affiliation:Center of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China.
Keywords:Cell-free DNA, biological characteristics, methodology, myocardial infarction.
Abstract:Much attention has been focused on cell-free DNA (cf-DNA) and its levels in the plasma, serum and body fluids of pregnant
women and patients with cancer or autoimmune disease, and those with severe trauma; however, knowledge of its biology and relationship
with myocardial infarction (MI) is still at an early stage. This paper introduces general aspects of the nomenclature, structure, function,
release mechanisms and methodology of cf-DNA and summarizes the current literature on concentration variation and regulatory
mechanisms in MI.
