Recent Advances in Mass Spectrometry for the Identification of Neurochemicals and their Metabolites in Biofluids

Author(s): Suresh Kumar Kailasa, Hui-Fen Wu.

Journal Name: Current Neuropharmacology

Volume 11 , Issue 4 , 2013

Become EABM
Become Reviewer

Abstract:

Recently, mass spectrometric related techniques have been widely applied for the identification and quantification of neurochemicals and their metabolites in biofluids. This article presents an overview of mass spectrometric techniques applied in the detection of neurological substances and their metabolites from biological samples. In addition, the advances of chromatographic methods (LC, GC and CE) coupled with mass spectrometric techniques for analysis of neurochemicals in pharmaceutical and biological samples are also discussed.

Keywords: Neurochemicals, LC-MS, GC-MS, CE-MS, MALDI-MS.

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 11
ISSUE: 4
Year: 2013
Page: [436 - 464]
Pages: 29
DOI: 10.2174/1570159X11311040007
Price: $58

Article Metrics

PDF: 2