Arterial hypertension is an epidemic currently affecting almost a billion people worldwide. The consequences
from high blood pressure vary, from peripheral arterial disease and chronic kidney failure to acute myocardial infarction
MicroRNAs (miRNAs) are small non-coding RNA molecules comprised of 22-26 nucleotides and provide posttranscriptional
protein expression regulation. The many biological processes in which they are implicated, such as cell
proliferation, apoptosis, metabolism, cell differentiation and morphogenesis confirms the functional significance of miRNAs.
It has been found that miRNAs are expressed in cardiovascular disorders and seem to be important players in the pathogenesis
of arterial hypertension. The elucidation of which miRNAs are key players and at what level is of high value since
it is necessary in order to better understand the mechanisms underlying hypertension, thus leading to better diagnostic
modalities and therapeutic regimes.