Abstract
Microbicides as a potential intervention strategy for preventing human immunodeficiency virus (HIV) transmission, provide women with a preventive option against HIV. For more than two decades, various studies have endeavored to find effective and safe microbicides, which would provide defense against HIV/AIDS. Microbicides include various agents having different mechanisms such as, disruption of cellular and microbial membranes (surfactants), restoration of the natural acidic protective pH of the vagina (acid buffers), interference interactions between HIV envelope proteins and cellular receptors (anionic polymers), and anti retroviral agents. This review presents the progress in development of microbicides in prevention of spread of HIV.
Keywords: AIDS, HIV, microbicides.
Current Drug Therapy
Title:Microbicides for Prevention of AIDS
Volume: 8 Issue: 1
Author(s): Ram S. Thakur and Arshad B. Khan
Affiliation:
Keywords: AIDS, HIV, microbicides.
Abstract: Microbicides as a potential intervention strategy for preventing human immunodeficiency virus (HIV) transmission, provide women with a preventive option against HIV. For more than two decades, various studies have endeavored to find effective and safe microbicides, which would provide defense against HIV/AIDS. Microbicides include various agents having different mechanisms such as, disruption of cellular and microbial membranes (surfactants), restoration of the natural acidic protective pH of the vagina (acid buffers), interference interactions between HIV envelope proteins and cellular receptors (anionic polymers), and anti retroviral agents. This review presents the progress in development of microbicides in prevention of spread of HIV.
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Cite this article as:
Thakur S. Ram and Khan B. Arshad, Microbicides for Prevention of AIDS, Current Drug Therapy 2013; 8 (1) . https://dx.doi.org/10.2174/1574885511308010007
DOI https://dx.doi.org/10.2174/1574885511308010007 |
Print ISSN 1574-8855 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3903 |
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