Title:Vascular Contribution to Alzheimer Disease: Predictors of Rapid Progression
VOLUME: 12 ISSUE: 4
Author(s):Marina Diomedi and Giulia Misaggi
Affiliation:Department of Neuroscience, University of Rome Tor Vergata, Italy.
Keywords:Alzheimer disease, cerebral blood flow, disease progression, hemodynamics, risk factors, transcranial Doppler.
Abstract:Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be
associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review
aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation
and progression, hypothesizing the possible vascular markers of rapidly progressive form.