A new and efficient method for the preparation of 3-amino-6-thieno[2,3-b]pyridine-2-carbohydrazides and
pyrido[3',2':4,5]thieno[3,2-d]pyramidinones from one-pot synthesis has been accomplished using 3-amino-6-thieno[2,3-
b]pyridines with hydrazine hydrate in ethanol under reflux. This new protocol has the advantages of easy availability and
high to excellent yields, simple experimental and work-up procedure. The synthesized compounds were confirmed
through spectral characterization using IR, 1H NMR, mass spectra and elemental analyses.