The Bioactive Compounds Obtained from Hawthorn, Chokeberry, Rosehip and Bilberry by Microfiltration
Mihaela Pascu (Neagu), Daniela - Elena Pascu, Gina Alina Traistaru, Andrei A. Bunaciu and Hassan Y. Aboul-Enein
Affiliation: Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, Tahrir Street, Dokki, Cairo 12311, EGYPT.
Keywords: Microfiltration, hawthorn, bilberry, chokeberry, rosehip, bioactive compounds, antioxidant activity.
The aim of this work is to obtain the bioactive compounds in hydroalcoholic extracts of hawthorn (Crataegus
oxyacantha, Fam. Rosaceae), chokeberry (Aronia melanocarpa, Fam. Rosaceae), rosehip (Rosa canina, Fam. Roseaceae)
and bilberry (Vaccinium myrtillus L., Fam. Ericaceae) by means of membrane separation process. Fruit extracts were
processed by microfiltration at ambient temperature and the bioactive compounds were subsequently characterized. The
microfiltration of plant extracts led to the concentration of biologically active compounds including polyphenols, procyanidins,
flavanols, and their separation from lower molecular weight compounds (amino acids, monosaccharides etc.),
passed into the microfiltration permeate solutions. To investigate the antioxidant activity of each plant extract, cupric ion
reduction antioxidant capacity (CUPRAC) spectrophotometric methodology was employed.
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