Current Bioactive Compounds

Adriano Mollica
Department of Pharmacy, University ”G. d' Annunzio” of Chieti-Pescara
Via dei Vestini 31
Chieti, 66100


The Bioactive Compounds Obtained from Hawthorn, Chokeberry, Rosehip and Bilberry by Microfiltration

Author(s): Mihaela Pascu (Neagu), Daniela - Elena Pascu, Gina Alina Traistaru, Andrei A. Bunaciu and Hassan Y. Aboul-Enein

Affiliation: Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, Tahrir Street, Dokki, Cairo 12311, EGYPT.

Keywords: Microfiltration, hawthorn, bilberry, chokeberry, rosehip, bioactive compounds, antioxidant activity.


The aim of this work is to obtain the bioactive compounds in hydroalcoholic extracts of hawthorn (Crataegus oxyacantha, Fam. Rosaceae), chokeberry (Aronia melanocarpa, Fam. Rosaceae), rosehip (Rosa canina, Fam. Roseaceae) and bilberry (Vaccinium myrtillus L., Fam. Ericaceae) by means of membrane separation process. Fruit extracts were processed by microfiltration at ambient temperature and the bioactive compounds were subsequently characterized. The microfiltration of plant extracts led to the concentration of biologically active compounds including polyphenols, procyanidins, flavanols, and their separation from lower molecular weight compounds (amino acids, monosaccharides etc.), passed into the microfiltration permeate solutions. To investigate the antioxidant activity of each plant extract, cupric ion reduction antioxidant capacity (CUPRAC) spectrophotometric methodology was employed.

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Article Details

Page: [137 - 142]
Pages: 6
DOI: 10.2174/22115528112019990008