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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Palladium Catalyzed Synthesis of Some Novel (Spirocycloalkenyl) Trimethylsilylacetylenes

Author(s): Manjunatha Achanna Venkatesha and HariPrasad Suresh

Volume 10, Issue 6, 2013

Page: [457 - 461] Pages: 5

DOI: 10.2174/15701786113109990007

Price: $65

Abstract

The synthesis of some novel (spirocycloalkenyl)trimethylsilylacetylenes employing the Sonogashira coupling reaction of the corresponding novel spirocycloalkenyliodides with trimethylsilylacetylene and Pd(PPh3)2Cl2/CuI catalyst in yields ranging 79-84% is reported. The compounds would serve as novel (spirocycloalkenyl)acetylenic anionic synthons.

Keywords: Acetylenic anionic synthons, enynes, silylacetylenes, spirocycloalkenes, Sonogashira coupling.


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