Despite the success in antimicrobial development, the rapid emergence of pathogenic bacteria resistance to
conventional antibiotics calls for an increased focus on the purification and characterization of new antimicrobials.
Antimicrobial peptides (AMPs) are promising candidates in future therapeutics. In addition to their broad array of
antimicrobial activity, these peptides show multi advent function to human health. The marine environment is relatively
poorly explored in terms of potential pharmaceuticals. It contains a tremendous organism diversity which would be a good
source of novel AMPs. In this present review we discuss recent antimicrobial peptides isolated from both marine fish and
marine invertebrates. We also mention the isolation and benefit of these marine-derived natural antibiotics.
Keywords: Antimicrobial peptides, marine fish, marine invertebrates, peptide structure and function.
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