Background: Gastroparesis is a disorder characterized by delayed gastric emptying of a meal in the absence of a
mechanical gastric outlet obstruction. Idiopathic gastroparesis is at least as common as diabetic gastroparesis in most case
series, and the true prevalence of gastroparesis is unknown.
Results: We report here an interesting case of idiopathic gastroparesis characterized by sudden onset in a female patient.
The diagnosis was confirmed by ultrasonographic study of gastric emptying and electrogastrography, by gastric
endoscopy/histology, and finally by allergy tests. The disorder was found to be due to a rare cause, namely an allergic
predisposition. In fact, our patient, who demonstrated an allergy to gold salts, had drunk a glass of a liqueur containing
gold flakes and developed an eosinophilic aggregation in the gastric mucosa observed at gastric endoscopy/histology. The
symptoms disappeared after steroid administration.
Conclusion: Our experience suggests that gastric histology and close enquiry into any history of allergy may be useful
diagnostic tools in cases of idiopathic gastroparesis.