Post-cardiac Arrest Syndrome in Children

Author(s): Dominique Biarent, Christine Fonteyne, Ariane Willems, Audrey Dupont.

Journal Name:Current Pediatric Reviews

Volume 9 , Issue 2 , 2013

Abstract:

Although sustained return of spontaneous circulation (ROSC) can be initially established after resuscitation in children, many of the children do not survive to discharge because they developped a post cardiac arrest syndrome.

The post-cardiac arrest syndrome includes systemic ischaemia/reperfusion response, post-cardiac arrest brain injury, postcardiac arrest myocardial dysfunction, and persistent precipitating pathology. The main cause of death after ROSC in children is brain injury.

Physiopathology and management are reviewed in regards of pediatric specificities. Management according to ABCDE includes airway and ventilation management, oxygen therapy, hemodynamic management with early goal directed therapy and protection of the brain against secondary injury by therapeutic hypothermia, management of seizures and control of glycemia.

Keywords: Post-cardiac arrest syndrome, ischemia reperfusion injury, children.

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Article Details

VOLUME: 9
ISSUE: 2
Year: 2013
Page: [125 - 133]
Pages: 9
DOI: 10.2174/1573396311309020005
Price: $58