Pharmacologic Role of Vitamin D Natural Products

Author(s): Pablo Urena-Torres, Jean Claude Souberbielle.

Journal Name: Current Vascular Pharmacology

Volume 12 , Issue 2 , 2014

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Abstract:

Vitamin D is essential for maintaining a healthy mineral and bone metabolism. It stimulates calcium and phosphate absorption by the intestine, regulates bone metabolism, and negatively controls PTH secretion through the endocrine action of its active metabolite calcitriol. Vitamin D also possesses a variety of effects unrelated with mineral and bone metabolism, including the regulation of arterial blood pressure and the prevention of cardiovascular complications, modulation of immunological responses, regulation of insulin production and prevention against diabetes, protection against certain cancers, renoprotection, and other beneficial actions. This article provides an update review of the sources and pharmacological characteristics of natural vitamin D compounds, their most clinical uses, and their most important clinical results.

Keywords: Bone, calcitriol, calcium, calcifediol, cholecalciferol, ergocalciferol, parathyroid hormone, phosphate.

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Article Details

VOLUME: 12
ISSUE: 2
Year: 2014
Page: [278 - 285]
Pages: 8
DOI: 10.2174/15701611113119990020
Price: $65

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