Quercetin (QC) is a typical plant flavonoid, possesses diverse pharmacologic effects including antiinflammatory,
antioxidant, anti-cancer, anti-anaphylaxis effects and against aging. However, the application of QC in
pharmaceutical field is limited due to its poor solubility, low bioavailability, poor permeability and instability. To improve
the bioavailability of QC, numerous approaches have been undertaken, involving the use of promising drug delivery systems
such as inclusion complexes, liposomes, nanoparticles or micelles, which appear to provide higher solubility and
bioavailability. Enhanced bioavailability of QC in the near future is likely to bring this product to the forefront of therapeutic
agents for treatment of human disease.
Keywords: Bioavilability, formulations, inclusion complexes, liposomes, micelles, nanoparticles, prodrug, quercetin, solubility.
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