A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized.
The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied.
The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives
against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than
that of rimantadine and amantadine.
Keywords: Adamantyamine, Antiviral, (H1N1)pdm09, Influenza, Monoterpenoid, Resistance.
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