Cells and Mediators of Inflammation in Acute Pancreatitis
Ramesh Kumar and Madhav Bhatia
Affiliation: Department of Biochemistry, Bundelkhand University, Jhansi (U.P.), India.
Acute pancreatitis (AP) is an acute inflammatory process of the pancreas which involves a complex cascade of
events initializing in pancreatic acinar cells. This, in turn leads to an inflammatory response, which results in the pathology
of acute pancreatitis. In this review, we describe the role of different cell types and inflammatory mediators in the
pathogenesis of acute pancreatitis.
Keywords: Acute pancreatitis, adhesion molecules, cells, chemokines, complements, cytokines, hydrogen sulphide, inflammation,
substance P, Toll-like receptors, transcription factors.
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