Antimicrobial treatment to attenuate expansion of abdominal aortic aneurysm has been suggested, especially
with the focus on Chlamydophila. In this systematic literature review only four randomized trials were identified. In two
small studies there is an indication of an effect of roxithromycin. In conclusion, however, more studies are needed, and
they must be properly sized based on power calculations as well as antimicrobially relevant. Such trials are on the way
both in Europe and the US, the results being awaited with interest.
Keywords: Aortic aneurysm, expansion, macrolide, tetracycline, antibiotic.
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