Allergy and Inflammation: An Immunological and Therapeutic Approach

Author(s): Shyamji Shukla , Harshita Shukla , Suneel Kumar , Ravindra P. Aharwal , Vaibhav K. Gupta , Sardul S. Sandhu .

Journal Name: Recent Patents on Inflammation & Allergy Drug Discovery

Volume 7 , Issue 2 , 2013

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Abstract:

All organisms are protected by their immune system but occasionally this system overreacts leading to allergic and inflammatory reactions in the body. These reactions are the starting points of various diseases like asthma, eczema and urticaria etc. They involve activation of T cells, release of histamines, toxic chemicals from mast cells and eosinophils respectively. Several chemically and naturally synthesized therapeutic agents are available for the treatment of these immunological diseases. The present review provides a detailed account of mechanism of allergic and inflammatory reactions, its types and various treatment strategies with a special focus on some recent patents in this field.

Keywords: Allergy, antibodies, hypersensitivity, IgE, inflammation, macrophage, therapeutic.

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Article Details

VOLUME: 7
ISSUE: 2
Year: 2013
Page: [135 - 150]
Pages: 16
DOI: 10.2174/1872213X11307020005
Price: $58

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