Cinchona Alkaloid-Catalyzed Stereoselective Carbon-Carbon Bond Forming Reactions
Srinivasarao A. Babu, Ramasamy V. Anand and Sripada S.V. Ramasastry
Affiliation: Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector 81, SAS Nagar, Mohali, Manauli P.O., Punjab, India, 140306.
This review provides insights into the patents available on one of the subfields of organocatalytic reactions,
specifically, the Cinchona alkaloids-based organocatalytic reactions, involving asymmetric C-C bond construction. Some
of the very important achievements in the asymmetric carbon-carbon bond formation by employing the Cinchona alkaloids-
based organocatalysts, one of the privileged classes of asymmetric catalysts, have been accentuated. The Cinchona
alkaloids-based enantio- and diastereoselective syntheses of a range of amino acid derivatives, bioactive molecules and
various synthetic intermediates with high efficiency are also highlighted.
Keywords: Asymmetric synthesis, Cinchona alkaloids, C-C bond formation, diastereoselectivity, enantioselectivity, organocatalysis.
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