Abstract
This review provides insights into the patents available on one of the subfields of organocatalytic reactions, specifically, the Cinchona alkaloids-based organocatalytic reactions, involving asymmetric C-C bond construction. Some of the very important achievements in the asymmetric carbon-carbon bond formation by employing the Cinchona alkaloids- based organocatalysts, one of the privileged classes of asymmetric catalysts, have been accentuated. The Cinchona alkaloids-based enantio- and diastereoselective syntheses of a range of amino acid derivatives, bioactive molecules and various synthetic intermediates with high efficiency are also highlighted.
Keywords: Asymmetric synthesis, Cinchona alkaloids, C-C bond formation, diastereoselectivity, enantioselectivity, organocatalysis.
29