Cinchona Alkaloid-Catalyzed Stereoselective Carbon-Carbon Bond Forming Reactions
Srinivasarao A. Babu, Ramasamy V. Anand and Sripada S.V. Ramasastry
Affiliation: Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector 81, SAS Nagar, Mohali, Manauli P.O., Punjab, India, 140306.
Keywords: Asymmetric synthesis, Cinchona alkaloids, C-C bond formation, diastereoselectivity, enantioselectivity, organocatalysis.
This review provides insights into the patents available on one of the subfields of organocatalytic reactions,
specifically, the Cinchona alkaloids-based organocatalytic reactions, involving asymmetric C-C bond construction. Some
of the very important achievements in the asymmetric carbon-carbon bond formation by employing the Cinchona alkaloids-
based organocatalysts, one of the privileged classes of asymmetric catalysts, have been accentuated. The Cinchona
alkaloids-based enantio- and diastereoselective syntheses of a range of amino acid derivatives, bioactive molecules and
various synthetic intermediates with high efficiency are also highlighted.
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